The purpose of this supplement is to facilitate researchers’ and clinicians’ use of the Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS). The NNNS was developed for the National Institutes of Health (NIH) to assess the neurobehavior of drug-exposed and high-risk infants. In the early 1990s, the NIH began the multisite (Detroit, Michigan; Memphis, Tennessee; Miami, Florida; and Providence, Rhode Island) Maternal Lifestyle Study (MLS), a prospective longitudinal study of in utero cocaine exposure, under the auspices of the National Institute of Child Health and Human Development Neonatal Research Network. The NNNS was developed for use in the MLS under a separate “Neurobehavioral Contract” from the National Institute on Drug Abuse to provide measures for the MLS that were sensitive to drug effects. Part of the mission of the contract was also the dissemination of the measures, a mission fulfilled, in part, by this supplement. The material provided here will...

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