Studies on 60 patients with megaloureters are described.

Thirty-two patients proved to have a defect in parasympathic innervation of the bladder. The defect in bladder function was the cause of ureteral dilatation. Bladder neck resection is the treatment of choice.

Fifteen patients proved to have defects in ureteral peristalsis as the cause of ureteral dilatation. Replacement of some of these defective ureters with narrowed segments of ileum has proved successful.

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