Difficulties in the proper use of the gelatin-viscosity test for assay of proteolytic activity have been discussed. It is the author's opinion that for routine clinical diagnostic studies the Andersen-Early test is sufficiently accurate and much simpler.

The considerations presented regarding measurement of pancreatic function and interpretation of data justify a critical attitude toward accepting some of the published data regarding normal and partial or progressive loss of pancreatic function. That such possibilities may exist is not denied, but the actual incidence must be determined by proper application and interpretation of results from sound methods for assay of pancreatic enzymes in duodenal fluid.

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