The present controlled study was to evaluate the effect of a feeding gastrostomy on the survival of infants with birth weights between 750 and 1,250 gm utilizing sequential analysis. A total of 122 infants were entered into the study at 48 to 72 hours after birth. A successful outcome was survival at 21 days. Of 54 matched pairs, 34 had a similar outcome and did not contribute to the sequential analysis. The outcome of the discordant pairs was recorded according to a prearranged scheme of sequential analysis. With the completion of the twentieth "untied" pair, the decision was made that mortality with gastrostomy was higher than that with routine feedings.

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