To the Editor.—

A conjugated bilirubin fraction in the neonate in excess of 20% of total serum bilirubin concentration or, alternatively, greaten than 1 mg/dL is cited as identifying cholestasis.1,2 It is common practice, therefore, for pediatricians to request fractionation of serum bilirubin at least once for any significantly jaundiced neonate. The patients described in the following case reports were seen 1 month apart at the same hospital with elevated conjugated bilirubin levels.


Patient 1

This 2,750-g girl was born after 36 weeks of gestation.

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